“If we could give every individual the right amount of nourishment and exercise, not too little and not too much, we would have found the safest way to health.” Hippocrates c. 460—377 B.C. (Greek Physician)
Microbes (viruses, bacteria and fungi) are part of our ecosystem as well as human bodies. The existence of life without them is not possible. We all live in a harmony with each other since the beginning of life on earth. Many of them actually help our immune system to get mature. It is only when our immune system is not performing optimally, that they get a chance to bypass it and bring on infections.
A unique species of fungus called “mushroom” is even used for eating and making herbal medicines. There are about 270 types of mushrooms (not all are edible though). There are more than one trillion bacteria on our skin, mucous membranes and even inside our tummy called normal flora or microbiome. They provide us protection against the invading pathogenic bacteria.
While most people focus, as they should, on social distancing, face coverings, hand washing and even self-isolation to protect against the deadly novel Coronavirus (SARS-CoV-2) now ravaging the country, too few are paying serious attention to two other factors critically important to the risk of developing a COVID-19 infection and its potential severity. Those factors are immunity (which should be boosted) and chronic inflammation (which should be suppressed). Acute inflammation on the other hand is protective mechanism of immune system but again, the exaggerated inflammatory response by the immune system starts damaging the body organs, so we need a balance.
The physiology of human immune system is very complex. But lately, we have been able to discover new paradigms of this complex system and we are still learning about it. Why do people get different severity of COVID-19 in a similar age group?
Because of our unhealthy, sedentary life style (with no exercise), bad eating habits, excessive sugar intake, stress, poor sleep, environmental toxins (in air, food, water) and artificial chemicals in everything we consume; put our immune system is under a constant threat resulting in its down regulation.
Old age, obesity, medications, chronic diseases, lack of nutrients and antioxidants also weaken our immune system. The list is quite long including EMF radiations. So due to a lack of balance, our immune system cannot withstand the attack of different microbes which results in infections. The food which is eaten by majority of population is devoid of micronutrients and rather contain empty calories.
If you get any symptoms of flu, don’t get panicked (you will just make the things worse by further suppressing your immunity with stress). Act sensibly by thinking positively…………hope for the best and prepare for the worst.
“The state of health or disease are the expressions of the success or failure experienced by the organism in its efforts to respond adaptively to environmental challenges” Rene Dubose, Famed Microbiologist 1965
By following the protocol given below, try to minimize the load on doctors and hospitals who are already over worked, dealing with more serious and critical patients. But if your symptoms are getting worse, then you are the candidate for medical advice and care in a hospital setting.
So far there has been no effective proven drug for COVID-19 treatment. Everything is in the air. The ones which are being used have a lots of side effects as well, so the results are not very satisfactory in severely and critically ill patients.
People who take antibiotics while suffering with a cold or flu often feel slightly better because antibiotics have a mild anti-inflammatory effect. But this benefit is far outweighed by the negative impact that antibiotics have on friendly bacteria that live throughout our digestive tract. They also prolong the recovery period.
I think that now it is the time for us to think out of the box and get to terms with this novel Coronavirus (SARS-CoV-2). Cold or flu will last as long as your immune system needs to create white blood cells and antibodies to over come it. If you work with your body instead of against it, COVID-19 might only last a few days without getting into a severe clinical condition.
“Le microbe ńest rien; Le terrain ćest tout!” (The microbe is nothing; its surrounding environment in the body is everything).” Antoine Béchamp Pierre Jacques (October 16, 1816 – April 15, 1908), who was a French scientist, now best known for breakthroughs in applied organic chemistry.
No anti-viral drug or vaccine has ever been developed which is 100% effective against any flu virus. As we don’t have a named drug or vaccine against the lethal Coronavirus (SARS-CoV-2), so our best bet should be to strengthen/ fortify the terrain to come to terms with it.
Our main target should be to augment the natural power of our immune system to help it deal with the infection itself, which seems to be rather more sensible approach as well. On one hand we need to boost our immunity to fight against COVID-19 and on the other hand we have to control exaggerated inflammatory response by by immune system to stop it going out of control; which could result in the production of “Cytokine Storm” which leads to the body attacking itself. This can be achieved by modulation of the immunity.
Infections increase the redox potential towards oxidative stress so does the COVID-19. If you have huge amount of oxidative stress, your immune system cant repair itself. So it starts to destroy you rather than the infection. Coronavirus (SARS-CoV-2) is causing huge amount of redox imbalance. Please click the link to read the details about modulating your immunity.
There are many myths and a lot of propaganda against the use of supplements (vitamins/ minerals/ anti oxidants) and herbs for COVID-19 due to the lack of proper awareness about the latest scientific research. Please do your own research (links given below). I have used them with an excellent outcome in severely ill patients. hey work in conjunction to build a strong immune response to coronavirus, so you can’t just pick and choose few things.
Some people have mild symptoms for the first few days and then suddenly get sicker. Some have fevers that go up and down repeatedly. Some are sick for two weeks straight, then have a few symptom-free days, then relapse. Some have lingering symptoms for months. So I would advise not to take risk and get yourself treated properly from start of the symptoms.
COVID-19 patients with poor prognosis have significantly lower serum levels of vitamin D compared to those with good prognosis, according to new data from a systematic review that pulled data from seven previous studies into its meta analysis. A total of 1,368 COVID-19 patients were included in the pooled results. Those with poor prognosis had an average vitamin D difference of 5.12 nmol/ L (2.05 ng/ mL), p=0.012, suggesting that even small corrections could have a beneficial impact on outcomes.
According to the authors: “Despite vitamin D promoting the expression of several inflammatory cytokines via T-cell inactivation and interferon-gamma activation 25, it simultaneously down-regulates pro-inflammatory markers interleukin-6 and tumor necrosis factor-alpha the two key cytokines involved with the development of the “cytokine storm” that precedes ARDS.”
A lots of complications are happening during the illness as well as after recovery. These include stroke, depression, anxiety, chronic fatigue, heart attack, heart failure, kidney failure and lung scarring causing breathing issues just to name a few. Recovered patients are already developing Type 1 Insulin dependent Diabetes Melitus. A more delayed autoimmune diseases develops in a significant subset of patients after few months. These include the patients of all severity and even asymptomatic patients. The appropriate treatment should target these problems to stop them happening at the first place and reduce severity if they do happen due to some reasons. The following supportive recommendation will address these issues along with helping to control the symptoms and clear the virus from the body.
The doses of vitamins and minerals are bit high to deal with the acute infection, but they are still within the upper limit. The doses mentioned are evidence based and are in clinical practice. It takes long time for toxicity to develop on very high doses of fat soluble vitamins anyways. So, you don’t have to worry about the dose. Just look at the severity of COVID-19, which could be lethal in few patients.
- Vitamin A produces IgA antibodies in respiratory mucosa (lining of bronchi and bronchioles), which provide the primary defence against the microbes by making a web around them. People with severe IgA deficiency get repeated cold and flu attacks. There are different forms of vitamin A available. Almost 30% of the population can’t convert carotenoid form of vitamin A (due to single nucleotide polymorphism or SNP in a gene) into the active form fat soluble form. Dose of Retinol or Retinoic acid: 15,000 to 25,000 IU x daily with food.
- Vitamin B complex help to make ATP and support the building of a strong immune system along with many other functions. Prefer to go for 5-formyl tetrahydro folate (folinic acid) or methylated folic acid (MTHF) in your B complex as it supports RBC, WBC and immune cells. Folic acid suppress NK cells. Dose: 2-4 x daily.
- Methylcobalamine (Methylated Vitamin B12) is a part of B complex but usually not included in proper form and amount in multi B complex supplement. Dose: 5,000 micrograms (5mg) x daily. If you are above 50 years of age, then take sublingual methylated B12 because the absorption decrease markedly as the age increases. Similarly medicines used for acidity also inhibit B12 absorption. Getting injectable form of methylated B12 is another option which is not very practical. If you have MTHFR mutation, then use hydroxycobalamine form of B12.
- Vitamin C is anti-oxidant, anti-inflammatory and supports natural immunity as well. It removes free radials as well as support other antioxidants, especially Glutathione (master intracellular antioxidant); by converting them back to their reduced form (after it has been oxidises) to be used again to remove ROS (reactive oxygen species) and balance the redox potential. It also prevents the inactivation of Nitric oxide (due to oxidative stress) which reduces the risk of clotting As vitamin C is used rapidly in redox reaction, so it has to be taken frequently. Lyposomal Vitamin C doesn’t cause diarrhea due to a better absorption. Dose: 1,000 mg after every 1-4 hours (depending upon severity) Continue taking upto bowel tolerance (start of diarrhea). Caution: A few people with deficiency of a enzyme called G6PD, cannot tolerate high dose of vitamin C. So if you develop the symptoms, then hold it off and start taking a lower dose of 500 mg at increased interval (2-4 hours), after the symptoms settle down. Alternatively use PQQ (given below).
- Vitamin D3 modulates immunity. Take Vitamin A first and give a gap of 6-8 hours before taking vitamin D3. Dose: 50,000 IU of D3 (Cholecalciferol) x once daily for 3 days with food. After that 50,000 IU after every 5 days or 5,0000 to 10,000 IU per day. It is much more preferable to take organic plant based, water soluble preparation. Alternatively, get direct sun exposure daily for 20-40 minutes depending upon you skin color. The form of Vitamin D used in a recent trial is Calcifediol. Click the link for dose and details. It has many advantages over Cholecalciferol including better absorption and quick action among others.
- Vitamin E modulates immunity. Look preferably for mixed tocotrienols (alpha, gamma and delta). d-alpha/ d-gamma or d-delta are the natural forms. Dose: 1,000 to 1,500 IU per day. Calculate the dose in mg
- Magnesium is an essential mineral to build a strong immune system. It is usually available in chelated form, combined with another compound which contains 20 % elemental magnesium. For example 500 mg of magnesium glycinate or bisglycinate (one of the good absorption form) contains 100 mg of elemental magnesium. There are almost 15 different forms of magnesium, any form can be used. Magnesium oxide causes diarrhea. So if you don’t have another option use one tablet at a time 2-3 times daily. Dose: 400 mg x daily (elemental magnesium) or 2,000 mg of chelated magnesium.
- Zinc (picolinate & oronate forms have good absorption) reduce virus replication by inhibiting RNA dependant RNA polymerase as well as supports immune system. Zinc gluconate is particularly effective against viruses. It also help the SOD (super oxide dismutase) to be reused in redox reaction. Take any form except zinc oxide (least absorbable form) . Dose: 100 – 500 mg x daily in divided doses throughout the day. 500 mg was used in recent clinical trial against COVID-!9 with a very good outcome.
- Zinc Ionophores help the zinc to enter inside the cells. Quercetin, EGCG (green tea extract) and Tonic water (contains quinine). Alternatively drink green tea three to four times a day.
- Selenium is an anti-oxidant and supports the immune system as well. Dose: 200 – 400 microgram x daily.
- Nebulization (steam inhalation) with Hydrogen Peroxide (preferably food or pharmaceutical grade) x 4 times daily. Regular hydrogen peroxide available in grocery stores is 3% in strength, while pharmacological grade is usually more than 6%. Watch the video about the method to use it.
- Cold pressed black seed oil is an anti-oxidant and very excellent immune modulator. Dose: One tea spoon x once daily.
- Garlic is anti-inflammatory, antioxidant and supports the immune system as well. It has antimicrobial peptides (to kill the pathogens) and helps to make natural glutathione (master intra-cellular antioxidant) production in the body as well.The best way is to take aged garlic preferably by Kayolic. Dose: 3-5 capsules x three times daily. Alternatively use crushed (pressed) organic garlic cloves (10 – 20) with water 2-3 times a day. Keep in air for 15-20 minutes at least before eating. It activates the chemical called Allicin inside garlic.
- Sodium Bicarbonate (NaHCO3) produce an alkaline environment which is not hospitable for viruses. Dose: One tea spoon in water x three times daily.
- N-acetyl Cysteine (NAC) is an anti-oxidant, mucolytic, cytokine storm suppressant, clots buster, precursor of glutathione. Dose: Start with 500 mg x twice daily and gradually increase every day if no symptoms of rash or vomiting. Maximum dose is 7,000 mg in one day according to University of Maryland medical center.
- Melatonin 6 mg x twice daily. After recovery taper off slowly.
- EGCG (green tea extract) is anti-inflammatory, antioxidant and stimulates AMPK (Adenosine 5 monophosphate activated protein kinase), which helps to promote innate immunity as well as regulates T-cells mediated immune response. It also stimulates ATP production, mitochondrial biogenesis and autophagy; all of which help eradicate the microbes from the body. Dose: 250 mg x twice daily. Metformin, Curcumin (chemical compound in turmeric) with black pepper (bioperine or piperine) to increase absorption; all activate AMPK as does the Resveratrol. The dose should be taken twice a day to keep AMPK activated.
- Ivermectin, Dose: 12 mg x twice on day one and then 12 mg x once daily with food for 4-5 days.
- Azythromycin if having breathlessness at rest. Dose: 250 mg x twice for one day followed by 250 mg once a day for next 4 days. Alternatively use Doxycycline. Dose: 200 mg for 5-7 days.
- HCQ (optional) Dose: 400 mg x twice for one day and then 200 mg x twice for next seven days.
Extra measures for severe disease (Choose two or more yourself for severe symptoms):
- PQQ (Pyroquinoline quinone). PQQ is many, many times stronger antioxidant than vitamin C. Dose: 20-40 mg x daily.
- *Liposomal Glutathine or L- Glutathione for oral intake. Dose: 2,000 mg x two to three times daily if well tolerated.
- Glutathione for nebulisation.
- Glutathione intranasal spray (10 %, 20 % or 30 %) compounded with Cyclodextrin. Dose: One spray in each nostril x three to four times a day.
- Elderberry Dose: 1-2 tea spoons x four times a day.
- Moducare (Beta setosterol and its glucoside sitosterolin in a 100:1). Dose : 20mg sterols/ 0.2 mg sterolins/ capsule. Take 2-4 Am and 1-2 PM. If weight more than 200 pounds, then take two capsules x three times a day.
- Ollicin (Olive leaf extract),
- Andographis Dose: 300 mg x four times daily
- Fish Oil (Omega 3 fatty acids). Dose: 3.000 mg daily.
- Quercetin 1,000 mg x four times daily
- Ganoderma Lucidum (Reishi Mushroom)
- English Ivy extract. Zarbees cough syrup’s main ingredient is English Ivy. Phytopharmica and ITI have it as well. Dose: 5-10 ml x 3-4 times daily, tandardised to 11% hederacoside C (4.7 mg/5ml).
- Statins or Red Yeast Rice Extract (HMG-COA Reductase inhibitors). Dose: Take twice daily or the respective product.
- Lidocaine liquid or gel for nebulisation. Do it in between the nebulisation with hydrogen peroxide. So it would be like doing nebulisation after every 2 hours, still better than being on a ventilator; isn’t it? Click the highlighted nebulisation in blue colour for details please. Mix 600 -1200 mg NAC and Quercetin (500 – 1,000 mg) in it as well.
- If you get the fever, don’t suppress it as it is body’s first line of defence. Reduce only if more than 103 degree Fahrenheit (39.4 C) in adults and 101 (38.3 C) in kids. Use cold compresses on head, arms and legs to ease up the symptoms.
- De-stress your self by thinking positively that “it would definitely resolve and I am going to be amongst the survivors of COVID-19.” Pray and meditate. Both of these are very important to boost your immunity by reducing stress. Sleep at least for 8-10 hours with 7-9 hours of night sleep. Go to bed early at 9PM.
- Buy a pulse oxymeter and keep a tract of your oxygen saturations. Contact the nearest hospital if your oxygen saturation (SaO2) is not maintained above 93% on mobilisation.
- Minimize your intake of all kinds of sugars sugary drinks (including sugar free). Use natural sweetener (stevia for your tea and coffee). Raw and natural honey can be used in small amounts.
- Consume moderate amount of animal proteins (milk/ yogurt and chicken soup) and increase your intake of vegetables and fresh salads.
- Keep yourself very well hydrated with 12 to 14 glasses of water. Mix fresh lemons in it, if you are not allergic to them. Various herbal teas/hot drinks can help with hydration and reducing symptoms; good choices include peppermint, ginger, eucalyptus, chamomile, and hot water with lemon, honey, and cinnamon.
- For sore throat, do gargles with pharmaceutical grade Hydrogen peroxide (one table spoon in one glass) and one tea spoon of salt in luke warm water (4-6 times a day). Hot teas and lozenges containing slippery elm are excellent demulcents (to relieve minor pain and inflammation of mucous membranes) for soothing irritated sore throats. Chamomile and peppermint teas are also helpful for soothing irritated sore throats, as are teas or infusions made from marshmallow root and licorice root, both of which can act as soothing demulcents.
- Avoid heavy, dense foods while sick and give your digestive system a break so the body can focus on healing.
- Consume mixed nuts, seeds, fresh salads, vegetables, moderate amounts of low glycemic index fruits or small amounts of high glycemic index fruits.
- Eat yogurt (probiotic) along with some form of fiber (prebiotic, a food for good bacteria) like fruits, vegetables, whole wheat, psyllium husk and chia seeds etc.
- Eat/ drink bone broth with mixed vegetables in it daily x two to three times daily.
- You can get many vitamins and minerals in a single product. You may have to add on a few extra supplements. Similarly you can also find a combination of immune modulating herbs. Only choose the herbs mentioned above as they modulate the immune system rather than only stimulating it.
- Ease your breathing: If you have a humidifier, use it. If not, a hot shower works.
- For respiratory congestion, use a humidifier, vaporizers, or steam inhalers, or spend time in steamy baths or showers. Dry air can exacerbate some symptoms such as coughing and chest tightness. Vaporizers and inhalers can also be used with decongestants or essential oils such as eucalyptus, menthol, peppermint, or frankincense. Nasal xylitol sprays are very beneficial, as is nasal irrigation using a neti pot or nasal irrigation bottle. Buffered saline is easy to make or can be purchased in packets and eliminates any irritation to delicate, irritated mucous membranes. Few patients feel better when they laid on their stomach (prone position). Salbutamol/ Albuterol inhaler (used by asthma patients) can also be used to ease breathing and reduce the cough.
- Try doing this breathing exercise: Take a deep breath, hold it for 5 seconds and release. Do that 5 times, then on the 6th time on the release, cough hard. Do that cycle twice, then lie on your front and take slightly deeper breaths for 10 minutes. Try to do it a couple of times a day.
- Irrigate your sinuses to help prevent the virus from taking hold. Xlear nasal spray offers a great alternative to those too young or squeamish for a neti pot. It contains xylitol and grapefruit seed extract, both known to have antimicrobial properties.
- Propolis is another great tool for your antiviral arsenal, with very little downside. Though clinical studies are limited, it appears to have antiviral and antimicrobial properties, is safe for use in kids and can also be found as a spray. It also appears to have anti-inflammatory properties, which may be a helpful remedy for symptom relief, should you actually get sick.
- Take a good cough suppressant 3-4 times a day. I would suggest to add a herbal cough syrup as well.
- If symptoms are severe, then switch off the sources of EMF (wifi router and phone data). Turn it on intermittently for short duration when necessary.
- Hydro-thermal (hot & cold) therapy protocol. Watch the video.
- Fire Cider Recipe for flu.
- Anti histamines (anti allergies) for runny nose or sneezing.
- Anti diarrheal tablets/ capsules if you get diarrhea after taking high dose of vitamin C.
- Low potassium increase the risk of Cytokine storm. So get your serum potassium level checked. Most of the population is low in potassium these days. Consume potassium rich foods if your level is mildly low and take some potassium supplement if very low provided you don’t have kidney failure and not on a potassium retaining tablets for blood pressure or heart failure. Get in touch with your doctor as well.
- Leeks, chives, onions and garlic have sulphur which support production of glutathione. But these should be in excess to a proper supplements the demand is very very high during the infection due to severe oxidative stress. A few people have sensitivity or intolerance to sulphur or sulpha drugs, so they can get headache, anxiety and disphoria etc. Taking Molybdenum with it will help to resove these symptoms.
- Consume food and drinks with high favonoids content like cocoa (dark chocolate), tea and berries etc.
- Don’t combine Azythromycin and HCQ in case of cardiac arrhythmias (irregular heart beat) or older than 50 years of age. Replace Azythromycin with Doxycycline instead (200 mg x twice for one day followed by 100 mg x twice daily for next 6-7 days).
- You don’t have to use everything from second part for severe symptoms. But if you are at higher risk or symptoms are very bad then try using 3-4 of them.
- Continue this protocol at 1/3 dosage for at least a year to prevent post recovery complications and autoimmune diseases.
How to Choose a good supplement?
Ideally look for:
- Preferably vegetarian (cellulose) or fish gelatin.
- One or more of these certifications “GMP, USDA Organic, ISO, SALSA, NSF, ISO, NPA, NSF, TGA.”
- Organic and gluten free (preferably).
- Cold pressed, extra virgin oils.
- Go for higher price range.
- Natural sources are much better than synthetic (but more expensive).
- Free from additives, fillers, artificial sweeteners and colors.
- Higher number and strength of ingredients.
- Extract rather than just dry powder.
- Acid resistant for probiotics.
- Always try to prefer capsules over tablets unless they are free from additives and have good absorption (mentioned on the label). It would be mentioned on the bottle or pack.
Cheap supplements cause more harm than good. Quality always comes with a price tag. Don’t buy a supplement if it does’t give full details of ingredients including their amounts.
Black seed oil:
Hydro-thermal (hot & cold) Therapy:
Statins/ Red Yeast Rice Extract:
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30316-8? fbclid=IwAR3L3eas3bV46EwraZCIw_exMH0IRggU0RbIzEtx0pbQG6QqadNWiW Ql-GA
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734787/ #:~:text=At%20the%20molecular%20level%2C%20statins,to%20its%20lowly%20gl ycosylated%20form
For any queries, please join the Facebook group. Please give your feedback as well in the group for the encouragement of other patients.
Online consultation for COVID-19: https://health-horizon.org/consultation-for-covid-19/
Send a message on what’s app number 00923094529836/ 00447549942269 as well.
Dr. Shahzad Faisal Chaudhary, MD
Fellowship in Regenerative, Anti-aging and Metabolic Medicine (USA)